Searchable abstracts of presentations at key conferences on calcified tissues

ba0003pp74 | Bone development/growth and fracture repair | ECTS2014

Bone turnover and FGF-23 levels in vitamin D-deficient critically ill patients with and without acute kidney injury

Schnedl Christian , Bisping Egbert , Zajic Paul , Dimai Hans Peter , Wagner Doris , Pieber Thomas R , Fahrleitner-Pammer Astrid , Amrein Karin

Introduction: Elevated FGF-23 serum levels are induced by hyperphosphatemia and are linked to poor skeletal mineralization and adverse outcomes including vascular calcification and mortality. Recently, it was shown that FGF-23 levels are substantially elevated in acute kidney injury (AKI), and that higher levels in AKI are associated with a greater risk of adverse outcomes.Methods: In 25 vitamin D deficient (25(OH)D <20 ng/ml) critically ill adults w...